I'm wondering whether samus can even hear sounds inside her suit that are harmful to her. Annihilator beam is used to open sonic locks on MP2: echoes, yet you cannot see a sonic boom with echo visor when you fire it, even though you see annihilator beam shots. In the best case scenario, if you saw a sonic boom with echo visor, you'd essentially go blind as it's so powerful, kinda alike Thardus overloading your thermal visor with a simple explosion of heat/phazon thingy. Her suit also has an innate danger meter, which rises whenever there's environmental damage like lava, acid and even electricity. Not forgetting all that noise coming from her own speed boosting and using sonic boom would break render her deaf, alongside massive explosions and whatnot, yet she's not. So these would support the possibility of her suit rendering harmful sounds to harmless. She's protected by her suit's energy force field and sound waves need to pass that energy field in order to reach her ears, not to mention the actual suit. It might be though that only loud noises are reduced in volume by her power suit, which would probably be the likely scenario, yet the suit itself can seemingly assess the danger coming from environment independently. In a case where Samus would feel herself falling asleep due to music box sounds, the power suit would most likely block off the sound as it's bonded to her biologically and if she thought of this sound being danger, it should be able to block this sound due to being harmful to her.
In any case, I can imagine she'd wake up if Luigi were to ram at her with Mega mushroom when she's asleep and then deal with that.
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To current match... as with adult Link, Mewtwo can use embargo to strip him from using any items. This should include sword and shield, as like with Blue bubble you're forced to put these items away whenever afflicted with it. For moveset:
Embargo/Aura Sphere/Recover/Calm mind (substitute)
Pretty self explanatory. Embargo first, then calm mind up around 2-3 times, then start hitting TL with Aura sphere that'll never miss. TL being unable to use anything besides Magic (and maybe sword and shield), he'd be forced to use Magic armor to protect himself from harm, which doesn't last that long. In case where he could still use sword and shield, hurricane spin would be his most damaging attack yet it'll leave him totally vulnerable afterwards. If he were to use both magic armor and hurricane spin in conjuction, it would drain his magic meter extremely fast, but wouldn't leave him vulnerable. However mewtwo would get ample time to set up. Hurricane spin is fairly powerful, but needs much time to charge up and it's hard to control, meaning unless magic armor is used from the beginning, TL cannot even charge up without getting beaten to the ground. Eventually Link's magic will wear out and it'll do so fairly quickly if he keeps using magic armor and hurricane spin, which can be dodged fairly easily cause Link is stuck on pre-spin attack position and can only move slowly on ground, giving mewtwo ample time to just get away from the range.
Embargo alone means TL will be in deep ****. Mewtwo >> characters relying on items. :3
My point was that clear, empty spaces=/=neutral. Smashers should know that of all people.
Rocky landscape with lava and acid and deadly atmosphere would be less neutral. =) Samus is at home in every kind of environment anyway, it would only hinder every other character besides her (well might not be able to speed boost, but who cares lol, just hyper mode and phazon everything organic and mutate them to a phazon monster rofl (lawl thardus)).
Empty space is as neutral as it can get. No disruptions there at all aka no random outside factors to influence the match, therefore it relies entirely on the capabilities of a character to use such landscape.