Konami does own the series at the end of the day, and their use of the IP in stuff like Pachinko machines does suggest they're willing to use it when it suits them. My own personal suspicion is that they're aware of the backlash after the split with Kojima (and especially after Survive) so they want to tread very carefully with future releases, and that given the company moving away from triple A gaming budgets they don't want the cost of any ports/remakes going out of control.
If I were in Konami's place and I wanted to ruthlessly maximize profits while minimizing the bad PR? I'd do a remake of Ghost Babel. It was originally a Game Boy Color title, so there's plenty to expand on, Kojima didn't direct it, no one can say a remake is ruining his vision, and it's an alternate universe release, so it wouldn't affect the mainline canon anyway. It would be a safe title that would still be new to most of the audience, and wouldn't step on too many people's toes overall.