Noms:
Cadence x10
Neku Sakuraba (The World Ends With You) x25
The Binding of Isaac is one of those games I don't give much consideration to being in Smash despite my obsession with it. I think that's because of how gruesome the game can be--while its cartoony artstyle mitigates it a lot, there's so much grim and gross stuff that I doubt Nintendo would consider it.
Heck,
the game's most iconic item, a shoe-in for a neutral special, is a laser
made of blood. I don't think Sakurai would give Isaac Brimstone, but without Brimstone, Isaac would honestly feel kinda incomplete. And this isn't even getting into the religious symbolism--I doubt they'd want to add a spirit of Satan (yes, they added Cuphead's Devil, but Isaac's version is literally named Satan and he has an inverted cross on his forehead; the religious overtones are a
bit stronger here).
That said, if Isaac
did get in, I think he could make for a good fighter with how many items he could use. Some specific ideas I have that I think are interesting are to give him a Final Smash where he turns into an angel and dunks opponents in a big chest with light beams (
referencing his boss fight in the Cathedral) and to give him a taunt where he throws the D6 forward--and if the D6 hits an item, it turns it into a different item (referencing the D6's ability to "reroll" items).
Now onto Isaac: IDK What would his series emblem be?
I'm partial towards a treasure chest myself, given its prominence in both gameplay and the story.
'nother question: Isaac's alts?
I second the idea of just using Isaac's other personas. Specifically, I think they'd go with:
Isaac
Magdalene's wig
Cain's eyepatch
Judas's fez
Eve's hair/mascara
Samson's hair/headband
??? (maybe include the X eyes, maybe not)
Demon (similar to Azazel, but based more on the demon version of Isaac from a couple pre-Rebirth endings)
And a question of my own: how likely do you think it'd be for them to include music from the original Flash release and not just Rebirth? Personally, I'd settle for just "My Innermost Apocalypse."