I saw the first 30 minutes of the Direct between work shifts (I stopped after the Game Boy and GBA games were shown) and nothing really wowed me aside from Pikmin 4.
Unless they're bringing back single player missions from the original (and if they did, then it wasn't shown), the first wave of Splatoon 3 DLC seems like a rip-off unless you really like the Squid Sisters - as far as I can tell, you're paying for an alternate lobby that's functionally identical to the normal lobby. (Though seeing it reminded me that I still need to play that game; maybe after I finish Pokemon Violet)
The Magolor content for Return to Dream Land looks neat, but it's not enough to convince me to double dip since I still have the Wii version. (I double dip on games occasionally, but it's usually if a game that I already have is part of a collection)
I'm waiting on reviews for Octopath Traveler 2 - my biggest issue is that all of the character interactions were saved for the post game, making the main game feel like eight completely separate adventures that only came together at the final boss. I'm hoping that's addressed here.
Glad to see that Advance Wars has a release date, and that Golden Sun is back in some form. I've heard that there's a Metroid Prime 1 remaster (though I have the game on the Gamecube and in the Wii version of Metroid Prime Trilogy, so I don't think I need it a third time) and a Zelda trailer, so I haven't seen them, and I'm not sure what else is in the last 10 minutes.
(There's also the Xenoblade 3 DLC, but I still need to finish Xenoblade 2 and 3 - I haven't been able to find the time for 100+ hour RPGs, and I wasn't a fan of what I played of Xenoblade 2)
Also, I'm a little worried that they've already run out of N64 games to announce for the online service, given that they're jumping straight to Game Boy and GBA.