Under normal circumstances, I would never dream to defy such a Quadrant of Cool, but I must.
Agreed that when Molina was on screen, Spiderman 2 was amazing (because Molina is amazing, not because of the movie itself). When he wasn't though, it was pretty awful. I also didn't like that Spidey losing his powers was just an unexplained plot device: he didn't want to be Spidey anymore, so they magically dissapear, and when he needs to save Mary Jane, they're conveniently back!
I have tons of other gripes that I won't bore you with, but the sheer absurdity of the following scene pretty much encapsulates the problems with Spidey 2:
http://www.youtube.com/watch?v=fwmCJsbwxIc&feature=related#t=7m47s