Peach Fair got nerfed. I'd poor one out for Peach mains but that move was honestly kind of stupid sometimes. She also got an F-Smash buff to compensate somewhat so it's not all loss for her.
Not sure how "gutted" Pichu really is. Those self-damage nerfs will certainly add up throughout a battle and the F-tilt nerf probably hurts, but he's still a small hurtbox with kill confirms and lightning loops. It'll definitely hurt him in the long run though.
Looks like this is the first patch with real nerfs though rather then just minor tweaks. Only top tiers seem to be effected by the nerf hammer and it wasn't all losses (Wolf having a Jab fix and buffed Shine seems nice and might even make him more fun to play in the long run, imo). They also seem to be sticking with the "buff more then nerf" philosophy looking at characters like Jr., Mac, and Captain Falcon gaining more then the top tiers lost.
There's tons of QoL changes overall though, especially to multihits and jabs, which is hugely appreciated.