We seem to be at the point where they need to start showing some actual stuff about BotW2, so I would guess, hopefully not incorrectly, that it would show up in the next Direct. Which already makes that a good Direct. Assuming it's not just another small snippit without a title.
And there's a lot of smoke about the Prime 1 remake/remaster, so... that will probably be in the Direct too. And they can't reasonably talk about an unannounced Prime game without at least acknowledging Prime 4. Now of course that doesn't mean we'd see anything from it... but it's not outside the realm of possibility that we would.
And just having those two games in a Direct would make it pretty great. Let alone stuff like the unannounced FE game, and, if the time is right, an AW release date and the Goldeneye reveal.