A lot of them will come next year, too. I think the animation with Vi and Jinx' origin story, the one with Ekko and the RPG set in Bilgewater might come first, as they've been properly teased via trailers - some are even taking the ending of the last Champion teaser as a sign of things to come.
Meanwhile, the fighting game and the top-down adventure one (with Ezreal, Annie and Blitzcrank) might take more time.
Regardless, they open a lot of doors for exploring the universe. I've talked about this before, but a K/DA rythm game would sell like hotcakes, for one. Or a Star Guardian one. Maybe a beat em' up/ hack n' slash set in PROJECT/PROGRAM. The new "visual novel" mode they made for Spirit Blossom makes me think they'd be successful with that, too.
Maybe a stealth game-
...OH GOD, METAL GEAR TEEMO