I would like to see it happen. I can see the situations and I think it's THEORETICALLY possible, I just don't think it's going to happen. basically, as samus you have to have the perfect solution every time DK jumps in.
all of bair goes through:
-both kinds of missiles
-charge shot at <half charge or so
-one hit of bomb (but who's really using it in that situation any way.
you can get under him with rising uair but he goes through the oter aerials, or gets away with only 3 damage taken from something like the first hit of fair.
the only defense I've seen is when a samus anticipates the bair and short missiles once, then delays the other missile punishing bair. then run through, try again, etc.
DK's f tilt goes through all the aforementioned projectiles as well, though power missiles cancel with f tilt. I've never seen a samus be able to handle a mix of f tilts and power shielding from DK. I feel like a DDD walking forward lol.
I know it's possible, but we're not here for the far away theory. we're here for doable strats that have been, or soon will be used for the matchup.
oh and before you mention up tilt, up tilt is a terribly unsafe option unless you're doing a hard read. DK's bair trades with it (making it a viable kill move for samus definitely) and if he air dodges then free downsmash ahoy. Just in case you wanted to bring up the other anti air lol.
oh and zair: it's pretty damn good against DK I guess. problem is if you full jump zair and DK airdodges in a full hop, he gets a free bair (or nair but not the others despite direction). If you falling zair, DK will cancel it with bair or just not get hit by it. I mean, he's above you lol. that's the basis of the situation. you jump up in anticipation of DK's aerials, and a smart DK won't let it phase him after the 2nd or 3rd time.