I certainly hope it does, but it's going to be extremely difficult. Batman Begins had a 48 mill opening weekend, however, it was released on a Wednesday so that number was pretty good back in '05. No one knew if the new Batman would suck so they were hesitant. Once people saw it, the general consensus was that it was amazing and, through word of mouth, it passed 200 mill domestic (over 4 times its opening weekend, indicating that it was well loved).
Now, I also think the Dark Knight will have an insane opening weekened because 1) three years of dvd sales and more word of mouth so everyone has seen Batman Begins 2) Heath Ledger died months ago and the trailer alone shows us how terrifying his last performance will be 3) the 2nd trailer for the Dark Knight has almost 10 million views on youtube BEFORE its release. I've never seen it that high before. Iron Man's trailer had about 4 mill views before it was released and it scored 98 mill in it's first three days. Based on this, the Dark Knight will break 150 mill. At the very least it'll be 120.