Well, I highly doubt this one looking at the sold copies of Punch-Out! for Wii.
http://www.vgchartz.com/gamedb/?name=Punch-Out&publisher=&platform=&genre=&minSales=0&results=200
If Little Mac and his franchise were still as popular, why do they only have around 0,24 million sold copies of the latest game for Wii?
Pit from Kid Icarus can be considered popular after a good comeback with Kid Icarus:Uprising having sold already 1,08 million copies. So after all, the comeback from Pit was way better than the comeback of Little Mac back in 2007.
Little Mac however can be considered popular because of his appearance in Brawl as an assist trophy making him with many rumours one of the most expected newcomers for SSB4.
About the roster itself:
I like that you consider Medusa over Palutena. No newcomer for the Yoshi series or the Wario series is however a bit disappointing. You consider an F-Zero newcomer while the series hasn't the same importance nowadays. However the Yoshi series and Wario series sell pretty well and there are even two Yoshi games on the way to come in 2014. These are just my two points on this one as I don't expect an F-Zero newcomer anymore and as I think a Yoshi or Wario newcomer could be more likely. It's pretty easy referring to sell numbers to explain why these two series could get a 2nd rep before F-Zero. Also the Yoshi series is in the roster since SSB64, same as for F-Zero.
I'm also surprised you expect the return of Roy and consider even Ike to stay. Beside that, you seem to pretty ignore the worldwide well received game Fire Emblem: Awakening.
I also don't see Tetra/ToonZelda coming. I feel like Impa may have a better chance if there were ever anyone of the development team considering a 5th representant.