Yeah, if a Wave 2 is announced, Isaac's chances become much better. If we see all third-parties Wave 1, and a Wave 2 is announced, I'm gonna call it a lock for Isaac, or as close as it gets. There couldn't possibly be any more big-name third-parties, and Sakurai would probably jump at the chance to give us more fan favorites. However, I also think Isaac (or a GS4 protagonist) is a basic lock for Wave 1 if we see a new GS game announced. If it's a remake, Isaac, of course. If it's GS4, it still could, and probably would be, Isaac, but if Sakurai really doesn't wanna mess with the Assist Trophies, then the GS4 protagonist would work fine.