For all we know, Mewtwo might be dubbed into having a more masculine voice for the English version of the movie, so it may lose its femininity altogether. Might as well call it an it so as to avoid the chance of being politically incorrect in the long run.
Personally, I'd like to see a moveset like one of the following:
[collapse="Mewtwo with Awakened Forme Final Smash"]
Neutral Special: Shadow Ball - Equivalent to his move in Melee.
Side Special: Confusion - Mewtwo grabs any projectile that flies towards him and launches it back at a faster speed. If used directly on an opponent, they become dazed and vulnerable to attack.
Up Special: Teleport - Equivalent to his move in Melee, except longer distance and allows attacks in his helpless state.
Down Special: Light Screen - Mewtwo creates a wall of light on both sides of him. Energy projectiles instantly disappear when they hit one. Physical projectiles disappear after passing through one and hitting the other. If used in the air, Mewtwo creates a horizonal barrier above him instead. This acts like a floating stage platform that allows physical projectiles to drop through.
Final Smash: Awakened Forme - Mewtwo changes his form into Newtwo, who flies around shooting Focus Blast projectiles. The projectiles fly in whichever direction Newtwo is currently flying, gaining size and losing its erratic movement when charged before being shot. Compare and contrast to a Super Sonic that moves slower and releases blood-red shadow balls.
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[collapse="Mewtwo & Newtwo"]
Mewtwo - Anti-projectile moveset
Neutral Special: Shadow Ball - Equivalent to his move in Melee.
Side Special: Confusion - Mewtwo grabs any projectile that flies towards him and launches it back at a faster speed. If used directly on an opponent, they become dazed and vulnerable to attack.
Up Special: Teleport - Equivalent to his move in Melee, except longer distance and allows attacks in his helpless state.
Down Special: Transform - Changes Mewtwo into Newtwo.
Newtwo - Anti-aerial moveset
Neutral Special: Psyshock - Holding down the button charges energy in Newtwo, doing more damage and being overall larger the longer it's charged. Releasing it makes Newtwo launch a pink, psychic projectile that behaves like a physical projectile.
Side Special: Telekinesis - Similar to Melee's Confusion, Newtwo flips an opponent up into the air. If used in the air, the opponent is sent flying upwards, but leaves them in a falling state. Bad for blocking an enemy's recovery, but good for setting up aerial combos.
Up Special: Parting Shot - Newtwo floats up into the air, having slight horizontal control. If it hits an opponent when initially used, Newtwo's ascent gives him superarmor and slight damage reduction.
Down Special: Transform - Changes Newtwo into Mewtwo.
Final Smash: Psystrike - Mewtwo of either form glows in a light-blue aura before sending out purple rings of energy from its body. If Mewtwo is within a certain radius of an opponent, the opponent is held in place in the air before being spectacularly slashed and distorted by a cloud of purple energy and rings. A final crescent shape of pink energy then launches the opponent away from Mewtwo, the direction depending on where the victim was relative to Mewtwo using the final smash.
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I also notice that I tend to zone out everything around me as I write movesets, as evident from just now noticing my phone's alarm having gone off while I worked.
