Missed Double Dragon because I never played it.
Missed Rygar, Defender, and GORF because I had never heard of nor played them.
Missed Duck Hunt because I only ever played other people's copies and thus never had exposure to the skeet shooting mode.
Missed the original Street Fighter because it took until SFII for Street Fighter to not look like Hot Garbage and I thought I was being thrown a curveball.
There were some educated guesses. Got Pole Position due to knowing Pole Position II, Worms Armageddon after seeing the holes in the environment, and after some brief confusion with Silent Hill I noticed the world wasn't covered in fog and got Resident Evil (you'd think there would have been more obvious cues, but having mostly ignored both series the technical use of fog is the thing that struck me the most about Silent Hill).
Then there were lucky guesses - Battlezone, Galaga '88, and Zaxxion.
The rest I knew for realsies. Most were obvious, but had a bit of a nostalgia trip with Pitfall, Food Fight, and Joust.