Ummm...ok, ill give some numbers
Regular Ganon punch does 32% (I thought it did 35% if you sweet spot?)
Reverse Ganon Punch does 35% (not sure if it has a sweet spot)
Up-Tilt does 27%
From the middle of Final Destination against MK
Reverse Ganon Punch KOs at 16%
Standard Ganon Punch KOs at 22%
Up-Tilt KOs at 39%!!
From the edge of Final Destination against MK
Reverse Ganon Punch KOs at 3%
Standard Ganon Punch KOs at 9%
Up-Tilt KOs at 20%!!
I also did some things with a stop watch...
i tested several times and i think these numbers are close to correct
Ganon punch takes 1 - 1.1 seconds from start to the punch
Up-Tilt takes 1.4 - 1.5 seconds from start to the heel explosion
sooo long story short, Ganon punch is better then Up-Tilt in every way i can see.. Up-Tilt may have a slight advantage in range...
But I can't jump off something and do a double reverse Up-Tilt
sorry for long post i got carried away in training mode