We can use this for basic match-up discussion, I was planning on making a detailed match-up guide/discussion thread some time down the road.
Easiest match-ups I find are characters without good tools to harass Ganon from far away and couple that with characters who can't kill him easily. Mario, Dr. Mario, Marth, and Lucina are good examples. I may argue that Ganon has advantage over them, but won't say anything for now.
Even match-ups, or match-ups close to even are characters as such as Ike, King Dedede, Donkey Kong, Little Mac, and Wario. These characters have good melee pressure tools and killing power, and Ganon has his own.