We usually do have a "What are your Most Anticipated [Year] Titles?" topic, you just got to it a bit early... but I'll allow it!
Anyways, as much as I want to be excited that a console is getting something like Huxley, I'm too worried about it. There haven't been any updates on the game in a long time, leading me to believe that it's going to get pushed back even further into 2008. Smash Bros of course is a given, I'll be happy to play with my friends online (as well as some of you guys), though I'm not letting myself get too excited over online because of the whole Friend Code business along with Nintendo not letting you get into specific games with specific friends in any of their games.
Anyhow, my most anticipated titles:
1) Fable 2
I loved the original Fable, and despite lacking a lot of the things that were promised when it was announced as Project Ego, it was still a blast to play through and had a lot of character. Aside from a few missing features, load times were days long. By days I mean around 2 minutes each, which was ridiculous, you encountered them every minute or so. Hopefully though things like that'll be sorted out in Fable 2, which is supposed finished story-wise and coding-wise, they're just beefing up the graphics and fixing bugs from now until whenever they decide to launch it in 2008.
2) Grand Theft Auto IV
Rockstar, why oh why did you announce a release date so long ago? It was a stupid move and all you did was disappoint a bunch of fans when you were announced "yeah, it's being pushed about 6 months." Now I have to wait till at least April? ****. Oh well, I'm sure it'll be worth it, I mean, I wouldn't want to know how many hours I wasted with San Andreas and Vice City, I'm sure GTAIV will not disappoint.
3) Super Smash Bros. Brawl
I already mumbled about this earlier in my post, so no more mumbling.
4) Halo Wars
I love RTSes, which rarely show up on consoles, I also love Halo, this should be great. Halo was originally going to be a RTS for the Mac, so this will be really interesting to see how it ends up. It's not being made by Bungie, either, but by the Age of Empire guys, Ensemble Studios.
5) Banjo Kazooie
Banjo is finally being revived on the 360. I was expecting this to hit in 2007, but at E3 Microsoft said they'd only be talking about games hitting in 2007, Banjo wasn't mentioned. If it's not 2008, I'll be seriously confused, though, it is Rare. The game should be gorgeous (Kameo and Viva Pinata were, and from the looks of it, it's following an art style closer to Viva Pinata) and will hopefully play great. The 360 doesn't have any decent platformers and Rare's Conkers BFD and Banjo 1 and 2 titles for the N64 were outstanding.