Lord_Deathborne
Smash Champion
Ganon is most likely already in the game, so I don't really feel the need to discuss his chances.
As far as other contenders for the Legend of Zelda spot, they're sadly quite low. My personal favorite is Aganhim to tell the truth, as he was the first major Zelda villain I squared off against, not mention he seems to me to have dealt out the most death (i.e. Link's Uncle, the King of Hyrule, the Priest, etc.). I also like Onox, Veran, and Vaati, each exhibiting an ominous aura in their own particular way. The Skull Kid was an interesting villain as well, but since you spent the least amount of time in actual battle with him (did it even count as a fight?), I'd say he's the least likely of the mentioned villains. Vaati currently has the best chances, having appeared in 3 games with Aganhim, Onox, and Veran pretty much tied as the runner-ups.
As far as other contenders for the Legend of Zelda spot, they're sadly quite low. My personal favorite is Aganhim to tell the truth, as he was the first major Zelda villain I squared off against, not mention he seems to me to have dealt out the most death (i.e. Link's Uncle, the King of Hyrule, the Priest, etc.). I also like Onox, Veran, and Vaati, each exhibiting an ominous aura in their own particular way. The Skull Kid was an interesting villain as well, but since you spent the least amount of time in actual battle with him (did it even count as a fight?), I'd say he's the least likely of the mentioned villains. Vaati currently has the best chances, having appeared in 3 games with Aganhim, Onox, and Veran pretty much tied as the runner-ups.