Its more like...
If you are using characters as they themselves function/appear in their games and more or less don't limit them by anything aside from obvious "game mechanic" [Such as say, how Mario can land a 100ft drop uninjured but a brush on the shin from a GOOMBA can kill him] or "hack/glitch" [such as a teleport glitch involving bottled bugs in OoT: that is something link can't normally do and is a product of a clear glitch, not the game world] type stuff, then SOME characters will have traits like this.
Notably characters that aren't really playable outside smash (Like Ganon, or the Black Knight from Path of Radiance) have special "rules" to them when it comes to how to fight them such as being either extremely resistant if not outright immune to things that arent attacks by other triforce[weapons/users] / blessed weapons, which is half of why they are so powerful in the first place (See: Twilight princess where ganon was impaled and banished, but shrugged it off like nothing because it wasnt the master sword/light arrows). Other characters, like Samus, just have so much HP / Resistance combined with HUGE firepower that it makes most fights trivial as she could obliterate most anything well before they even scratch her, if they even hit her thanks to the speed booster / shinespark.