Emulation problems, please help!

[Dark_Knight_X1]

I'm using Dolphin 5.0, and Melee is acting up. It's in a "perfect state" according to the emulator, but when I open Melee up, it says the following:

Note: Option "EFBScale" is overridden by game ini.
Warning: Opening the graphics configuration will reset settings and might cause issues!
Dolphin OGL Video Backend.
Video info: NVIDIA Corporation, GeForce GT 430/PCIe/SSE2, 4.50 NVIDIA 355.82

I have a Windows 10 computer. What the heck does the following in yellow mean?
Edit: I also repeated the procedure with Dolphin 4.0 and got the same results.
Edit 2: What's WORSE is that I disabled on-screen messages and it says "Disc not read" and it shows random series of numbers

 

[All Things Gaming 6]

As far as I know, that doesn't mean anything. I get the same message & Melee runs with no problems. Just disable On-Screen Display Messages.

 

[Dark_Knight_X1]

As far as I know, that doesn't mean anything. I get the same message & Melee runs with no problems. Just disable On-Screen Display Messages.

It doesn't read my ISO when I launch it period, which is the problem, but thank you for the information about on screen messages.

 

[All Things Gaming 6]

It doesn't read my ISO when I launch it period, which is the problem, but thank you for the information about on screen messages.

Okay, well then I can't help you.

At least it's nice to see another Mewtwo main on the forums.

 

[Dolla Pills]

I'm guessing it's an issue with your iso rather than with Dolphin