Outside of the top two best setups (FHQ and
THD), I occasionally do some alternatives:
AHD = All-Around Tradeoff, Home-Run Bat, Desperate Immortal. It is essentially a more extreme version of the THD strategy. Lucario is the only character I'd even remotely recommend with this setting. It is extremely risky, but lots of fun having maximum aura almost all the time.
FHD = First Striker, Home-Run Bat, Desperate Immortal. This is a compromise of the FHQ and THD setups. It allows for two chances to be invincible per ticket, and is ideal for characters who can quickly inflict self-damage. My highest score so far with this particular setup is 55 turns with Charizard, though it will never compete with my top ten characters using other strategies. I modified his specials to Fireball Cannon for sake of getting first strike easily and Blast Burn so I can build up my own damage more quickly.
Pretty much anything else I try is mostly a modification of FHQ and/or THD. I have experimented with numerous other setups not involving the Home-Run Bat, substituting out for Critical Hitter and/or other weapons, but I am 99.9% convinced that no setup without the Home-Run Bat will ever be as efficient as any set up with it, especially for quickly dispatching giants and metals.